Stress, Chronic Stress, Burnout

Chronic Stress

The difference Between STress, Chronic Stress and Burnout

Stress is a natural response to a perceived threat or challenge, and it is designed to help us deal with these situations by releasing hormones that increase heart rate, blood pressure, and breathing rate. This is known as the “fight or flight” response, which is triggered by the release of stress hormones such as cortisol and adrenaline. These hormones are produced by the adrenal glands, which are located on top of the kidneys.

When a stressor is detected, the hypothalamus in the brain releases a hormone called corticotropin-releasing hormone (CRH), which signals the pituitary gland to release adrenocorticotropic hormone (ACTH). ACTH then stimulates the adrenal glands to release cortisol and adrenaline into the bloodstream.


Cortisol is a steroid hormone that is involved in a wide range of physiological processes, including the regulation of blood sugar levels, the immune response, and the metabolism of fats, carbohydrates, and proteins. In response to stress, cortisol levels increase, which can have both positive and negative effects on the body.

In the short-term, cortisol helps the body deal with stress by increasing heart rate, blood pressure, and breathing rate. It also suppresses the immune system, which can help the body fight infections and heal wounds.

Chronic stress

However, when cortisol levels remain elevated over a prolonged period of time, as in the case of chronic stress, it can have negative effects on the body. Chronic stress refers to a prolonged period of stress that is typically related to ongoing stressors, such as work-related stress, financial stress, or relationship stress. Chronic stress can cause a range of physical and emotional symptoms, including heart disease, diabetes, fatigue, irritability, anxiety, depression, and physical health problems.

Chronic stress can also lead to a dysregulation of the HPA (hypothalamic-pituitary-adrenal) axis, which is the system responsible for regulating the body’s stress response. This dysregulation can lead to changes in the levels of cortisol and other stress hormones, which can have a negative impact on the immune system, as well as on other physiological systems.


Burnout, on the other hand, is a state of emotional, physical, and mental exhaustion that is typically caused by chronic stress that exceeds an individual’s coping resources. Burnout is often associated with work-related stress, but it can also result from other stressors, such as caregiving responsibilities or personal life stress.

Stress burnout is thought to be caused by a dysregulation of the body’s stress response system. Prolonged exposure to stressors can lead to an overactivation of the hypothalamic-pituitary-adrenal (HPA) axis, which is the system responsible for regulating the body’s stress response.

Burnout is characterized by a sense of detachment or cynicism, feelings of reduced effectiveness or accomplishment, and a sense of emotional depletion. Other symptoms of burnout may include chronic fatigue, insomnia, and physical health problems such as headaches and gastrointestinal issues.

While chronic stress and burnout are related, burnout is often considered to be a more severe form of stress. Burnout typically develops gradually over time as an individual’s coping resources become depleted, whereas chronic stress can develop more quickly and may be more manageable if the individual has effective coping mechanisms in place.

Scroll to Top